Drug-Induced Peripheral Neuropathy

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چکیده

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Integrated Systems Pharmacology Analysis of Clinical Drug-Induced Peripheral Neuropathy

A systems pharmacology approach was undertaken to define and identify the proteins/genes significantly associated with clinical incidence and severity of drug-induced peripheral neuropathy (DIPN). Pharmacological networks of 234 DIPN drugs, their known targets (both intended and unintended), and the intermediator proteins/genes interacting with these drugs via their known targets were examined....

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ژورنال

عنوان ژورنال: Basic & Clinical Pharmacology & Toxicology

سال: 2014

ISSN: 1742-7835

DOI: 10.1111/bcpt.12261